Decrease in Cortical Benzodiazepine Receptors in Symptomatic Patients With Leukoaraiosis

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Decrease in Cortical Benzodiazepine Receptors in Symptomatic Patients With Leukoaraiosis

Background and Purpose—[C]flumazenil (FMZ), a ligand that selectively binds to the central benzodiazepine receptor in the neuronal membrane, is useful for evaluating neuronal viability in a positron emission tomography (PET) scan. Using this ligand, we investigated whether there was a correlation between neuronal integrity in various brain structures and dementia in patients with leukoaraiosis....

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Decrease in cortical benzodiazepine receptors in symptomatic patients with leukoaraiosis: a positron emission tomography study.

BACKGROUND AND PURPOSE [11C]flumazenil (FMZ), a ligand that selectively binds to the central benzodiazepine receptor in the neuronal membrane, is useful for evaluating neuronal viability in a positron emission tomography (PET) scan. Using this ligand, we investigated whether there was a correlation between neuronal integrity in various brain structures and dementia in patients with leukoaraiosi...

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ژورنال

عنوان ژورنال: Stroke

سال: 2004

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.0000122624.32167.e0